The best areas for a road trip in Italy: 5 Best Italian Itineraries

Planning a road trip to Italy? Look no further! I am Italian, and I love taking road trips. So I wrote this post to give you some amazing Italy road trip ideas for your next trip.

Enjoy!

5 Itinerary for the Best Road trips in Italy

1. Amalfi Coast road trip Itinerary (7 days)

The Amalfi Coast is definitely one of the best areas for a road trip in Italy. It features stunning coastlines and picturesque towns, which you can explore while driving along winding roads. 

So, here is a brief 7-day itinerary road trip along the Amalfi Coast for an unforgettable experience. 

You may want to check out my post on renting a car in Naples as well.

Day 1: Naples to Sorrento

Start your road trip in Naples and drive to Sorrento, a charming town known for its lemon groves and stunning views of the Bay of Naples. 

Sorrento is a great place to start your Amalfi Coast adventure, as it is located at the beginning of the coastal road and is easily accessible from Naples.

Spend the day exploring the town’s narrow streets, visiting the local markets, and enjoying the local cuisine. And don’t forget to try the famous limoncello, a sweet lemon liqueur made from the lemons grown in the surrounding area.

Also, if you are up to a more adventurous activity go for a hike along the paved Punta Campanella for spectacular sea views.

Day 2: Sorrento to Positano

Drive along the scenic coastal road to Positano, a picturesque town perched on the cliffs overlooking the sea.

The drive from Sorrento to Positano is one of the most beautiful in the world, with stunning views of the sea and the rugged coastline.

Spend the day exploring the town’s charming streets lined up with colorful houses, visiting the local shops, and enjoying the local cuisine.

Day 3: Positano 

Start your day with a refreshing dip in Positano’s main beach, Marina Grande, and immerse in the city’s carefree and relaxing ambiance. 

After enjoying Positano’s beach and delicious cuisine, trek the famous Il Sentiero degli Dei hiking trail in the hills behind Positano for an adventurous activity.

Day 4: Positano to Amalfi

Continue your road trip to Amalfi, a historic town known for its stunning cathedral and beautiful beaches. The drive from Positano to Amalfi is another scenic one, with breathtaking views of the azure waters of the Tyrrhenian Sea. 

So, be sure to schedule your drive as early as possible because you will surely stop several times to enjoy spectacular views and capture beautiful photos simply.

Then, spend the day strolling the town’s charming streets, browsing the various shops and markets, and enjoying delicious local seafood.

Day 5: Amalfi 

Start your day with a walk through the colorful streets of Amalfi and take in the architecture and sights. Be sure to visit the Duomo di Amalfi, a 9th-century cathedral.

Grab some lunch at one of the many traditional restaurants in the heart of town, and enjoy a relaxing stroll around boutique stores and souvenir shops.

Visit the Amalfi Handmade Paper Museum to learn more about the town’s culture, history and significance in the paper industry.

In the evening, head down to the waterfront to relax and enjoy the beautiful sunset over the Tyrrhenian Sea.

Day 6: Amalfi to Salerno

Drive to Salerno, a historic town known for its beautiful old town and stunning cathedral. 

Salerno is a great place to spend a day exploring lively streets and local markets and dine at excellent restaurants serving delicious authentic southern cuisine. 

Also, take a romantic stroll along the Lungomare Trieste, a seaside promenade stretching from the old town to the harbor of Piazza della Concordia, to enjoy the best views of the Gulf of Salerno. 

Day 7: Salerno to Naples

Naples is a great city to end your Amalfi Coast road trip, with plenty of things to see and do. For instance, some significant attractions to explore while in Naples are Piazza del Plebiscito, Palazzo Reale, and Teatro di San Carlo.

However, while in Naples, the must thing to do is try the famous Neapolitan pizza, a delicious pizza made with fresh ingredients and cooked in a wood-fired oven.

2. Tuscany road trip itinerary (10 days)

Tuscany is a region in central Italy known for its beautiful landscapes, history, and delicious cuisine.

One of the best ways to explore the region is by road trip since it allows you to see its many beautiful spots at your own pace and even discover hidden gems.

So, let’s see a 10-day road trip itinerary that will take you through some of Tuscany’s most beautiful and historic towns.

Day 1: Florence

Start your Tuscany road trip in Florence. However, do note that while in the city, a car might not be needed. 

So, on the first day, simply explore the city’s stunning architecture while strolling around, browse local shops, and later try delicious food at one of the many restaurants in the historic center.

Also, read: Where to stay in Florence

Day 2: Florence

Start your Tuscany road trip in Florence. However, do note that while in the city, a car might not be needed. 

Still, rent the car from the airport or another independent rental car service, find a suitable parking spot, and start your Tuscany adventure.

On the first day, explore the city’s stunning architecture while strolling around, browse local shops, and later try delicious food at one of the many restaurants in the historic center.

You can check out my 2-day Florence Itinerary for more detailed information on what to see in Florence.

Day 3: Florence to Montepulciano

On the third day, drive to the charming hilltop town of Montepulciano, known for its stunning views of the surrounding countryside. 

So, be sure to include plenty of time for your drive because, frankly, you might desire to stop several times just to take in the breathtaking views of rural Italy.

Once you arrive in the city, spend the rest of your day strolling along the historic center and charming cobblestone streets to discover beautiful Renaissance architecture.

Day 4: Montepulciano

Start your day by exploring the historic center, where you’ll find the Palazzo Comunale, the Cathedral of Santa Maria Assunta, and the Piazza Grande.

Then head to one of the many local wineries to sample the famous Vino Nobile di Montepulciano. 

Don’t forget to take in the stunning and panoramic views of the Val d’Orcia and Val di Chiana from the town’s scenic viewpoints.

Day 5: Day Trip to Val d’Orcia

Drive to the UNESCO World Heritage Site Val d’Orcia, a stunning region with rolling hills, picturesque towns, and beautiful countryside. 

First, explore the Castello Banfi IL Borgo, Europe’s largest wine producer, and enjoy lunch at their lovely restaurant.

Lastly, before going back to Montepulciano, visit the hilltop of Montalcino to indulge in Italy’s most famous wine Brunello di Montalcino and immerse in the beautiful landscapes of vineyards.

Day 6: Montepulciano to Siena

On the sixth day, head towards Siena, a UNESCO-listed medieval town an hour away from Montepulciano.

Visit the Piazza del Camp, one of the most famous squares in Italy, and the Siena Cathedral, a stunning example of Italian Gothic architecture.

Siena is also known for its cuisine, so be sure to try some of the local specialties, such as pici pasta and panforte.

Day 7: Siena to San Gimignano

Drive towards the small medieval town of San Gimignano, about an hour away from Siena. 

The town is famous for its towers built by wealthy families in the 14th century. You can also explore the town’s narrow streets and alleys, visit the Piazza della Cisterna, and climb the Torre Grossa for panoramic views of the surrounding countryside.

San Gimignano is also known for its white wine, Vernaccia di San Gimignano, so be sure to taste it at one of the many wineries in the area.

Day 8: San Gimignano to Pisa

Head towards Pisa, which is about an hour and a half away. 

Pisa is famous for its iconic Leaning Tower and is a must-see attraction. You can also visit the Piazza dei Miracoli, a UNESCO World Heritage Site and home to the Cathedral of Santa Maria Assunta, the Baptistery, and the Camposanto Monumentale.

Day 9: Pisa to Lucca

Lucca is only thirty minutes away from Pisa, so you could split the day between the two cities or leave early to explore Lucca fully.

At Lucca, you can walk or bike along the top of the city, which offers stunning views of the city and its surroundings. Lucca is also famous for its churches, such as the Cathedral of San Martino and the Church of San Michele in Foro.

Be sure to try some local cuisine, such as Buccellato, sweet bread, and Lucca speciality.

Day 10: Lucca to Florence

On the last day, depending on your schedule, you can spend some time in Lucca before returning to Florence. The drive back is about an hour, so arrange your day’s activities accordingly. 

3. Sicily road trip itinerary (10 days) 

Sicily, the largest island in the Mediterranean, is a land of stunning natural beauty, rich history, and delicious food. 

So, a road trip through this enchanting island is the perfect way to explore its diverse landscapes and discover its fascinating cultural heritage.

Let’s explore a detailed 10-day road trip itinerary for an unforgettable adventure.

Day 1: Palermo

Palermo, the capital city of Sicily, is the perfect starting point for a 10-day road trip on this beautiful island. 

On day one, explore the historic city center, a mix of different cultures and styles. Visit the impressive Cathedral, the Quattro Canti, and the Royal Palace. Wander through the colorful markets and try local street food, such as arancini and panelle.

In the evening, head to the lively Vucciria market for a drink while listening to funky live music.

Day 2: Palermo

On day two, take a short drive from Palermo to the charming town of Monreale. Here, you can visit the stunning Monreale Cathedral, famous for its intricate mosaics and beautiful architecture.

Afterward, head back to Palermo and explore the picturesque fishing village of Mondello, which is a short drive away. Relax on the beach, stroll along the promenade, and enjoy fresh seafood at one of the many restaurants. 

Later, be sure to check out Palermo’s vibrant nightlife.

Day 3: Palermo to Milazzo via Cefalù 

Head east towards Milazzo, with a stop in the charming coastal town of Cefalu along the way. Celafu is known for its beautiful beaches, historic old town, and stunning Cathedral, which boasts impressive Byzantine mosaics. 

Stroll through the narrow streets of the old town, enjoy a gelato by the sea, and soak up the relaxed atmosphere of this picturesque town.

Afterward, continue your journey to Milazzo, a bustling port town with rich history and plenty of sights to explore.

Day 4: Trip to the Aeolian Islands

Take a break from driving and hop on a ferry from Milazzo to the stunning Aeolian Islands. This archipelago of seven islands is UNESCO-listed and offers some of the most breathtaking scenery in Italy.

Explore the volcanic island of Stromboli, famous for its active volcano, or head to the island of Lipari, the largest of the Aeolian Islands, and discover its charming old town and beautiful beaches.

Day 5: Milazzo to Taormina

Located just a short drive from Milazzo, Taormina is perched on a hill overlooking the Ionian Sea and offers spectacular views of Mount Etna.

Spend the day exploring the town’s winding streets, ancient ruins, and beautiful gardens. Don’t miss the chance to visit the iconic Teatro Greco, a well-preserved ancient Greek theater that still hosts performances today.

Day 6: Taormina to Catania

Head towards Catania, a vibrant city known for its baroque architecture, lively markets, and delicious street food.

Spend the day exploring the city’s impressive landmarks, including the Piazza del Duomo, the Castello Ursino, and the Fontana dell’Elefante. Also, don’t miss the chance to sample Catania’s famous street food, such as arancini, cannoli, and granita.

In the evening, head to one of the city’s popular bars or clubs to experience Catania’s lively nightlife scene.

Day 7: Day Trip to Mount Etna

Take a day trip to Mount Etna, one of the most active volcanoes in the world. It is just a short drive from Catania and is a must-visit spot for nature lovers and adventure seekers.

Pick one of the many guided tours to fully enjoy the volcano’s beautiful landscapes, such as craters, lava flows, and ancient forests.

If you’re feeling adventurous, you can even hike to the volcano’s summit for spectacular views of the surrounding countryside.

Also, don’t forget to sample some of the local wines produced on the slopes of Mount Etna, known for their unique flavor and aroma.

Day 8: Catania to Agrigento

The journey from Catania to Agrigento will take you through some of Sicily’s most beautiful and historic parts. Along the way, you’ll have the opportunity to visit the ancient city of Syracuse, with its impressive Greek theater and Roman amphitheater. 

You’ll also pass through the charming town of Noto, known for its beautiful Baroque architecture, and the scenic fishing village of Marzamemi.

Finally, as you approach Agrigento, you’ll see the stunning Valley of the Temples, a UNESCO-listed site featuring some of the best-preserved ancient Greek ruins in the world.

Day 9: Day trip to Scala dei Turchi

Take a day trip to Scala dei Turchi, a stunning white cliff formation on the coast of Realmonte. The name translates to “Stairs of the Turks” and refers to the historical invasions of the Saracens. 

The unique white color of the cliff is due to the presence of marl, a sedimentary rock easily eroded by the sea. 

You can spend the day relaxing on the beach, swimming in crystal-clear waters and exploring the cliffs.

Day 10: Agrigento to Palermo

After an adventurous road trip around Sicily, make your way back to Palermo. The drive from Agrigento is about two hours. So be sure to schedule your trip according to your flight, ferry, or train back home.

4. Sardinia road trip itinerary (7 days)

Sardinia, the second-largest island in the Mediterranean Sea, is a hidden gem waiting to be explored. With crystal-clear waters, a rugged coastline, and rich history, Sardinia is the perfect destination for a road trip adventure. 

Below you can find a 7-day road trip itinerary starting from Calgiari and finishing in Olbia, with must-sea sights and experiences along the way. 

Day 1: Cagliari

Start your Sardinia road trip from the charming city of Cagliari. 

Begin your day by exploring the historic center Castello, perched on a hill overlooking the city. Wander through the narrow streets and alleys, admiring the colorful buildings and stunning sea views.

Visit the Cathedral of Santa Maria and the Bastione di Saint Remy, a panoramic terrace offering breathtaking cityscapes. Then head to the Poetto beach, on the city’s most popular beaches, to soak up the sun and enjoy the crystal-clear waters of the Mediterranean.

Day 2: Day trip to the Beaches of the South

Take a day trip to the gorgeous beaches of the south. Start by driving to Chia, a small village with pristine waters and spend some time relaxing and swimming in the turquoise sea.

Next, head to Tuerredda, a secluded beach with white sand and clear waters, perfect for snorkeling and diving. 

Finally, make your way to Porto Pino, a long stretch of sandy beach surrounded by dunes and pine forests.

Day 3: Cagliari to Barumini

On the third day, head towards the small town of Barumini. 

Along the way, make a stop at the Nuraghe di Arrubiu, a well-reserved complex dating back to the Bronze Age. 

Continue your journey to Barumini, where you can visit the Su Nuraxi archaeological site and one of the most important Nuragic settlements on the island. Take a guided tour to learn more about its history and explore the area fully.

Day 4: Barumini to Bosa via Oristano

Before arriving in the beautiful town of Bosa, stop by the historic city of Oristano. Visit the charming town center and the Torregrande beach to marvel at its crystal-clear waters and white sand.

Then continue your journey to Bosa, the picturesque town on the banks of the Temo River. Explore the colorful houses and charming alleys, and climb up the Malaspina Castle for panoramic views of the surrounding area.

Day 5: Day trip to Alghero

Located on the northwest coast of the island, Alghero is known for its stunning beaches, historic center, and Catalan heritage.

Stroll along the seafront promenade, visit the 16th-century Aragonese Tower and explore beautiful alleys with colorful houses and medieval architecture. 

Also, don’t miss the chance to try local seafood specialties, like bottarga and lobster spaghetti.

Day 6: Bosa to Porto Cervo

For a change of mood, drive from the charming town of Bosa to the luxurious resort town of Porto Cervo. Along the way, stop at the stunning beaches of Is Arutas and Mari Ermi, known for their unique white quartz sand. 

Then continue towards Porto Cervo and make your way to Costa Smeralda, known for its high-end boutiques, restaurants, and yachts. 

Take a stroll along the marina and enjoy the stunning views of the Mediterranean Sea.

Day 7: Porto Cervo to Olbia

On the last day, make your way to Olbia, where you can either take a ferry back to the mainland or a flight back home.

5. Puglia road trip itinerary (7 days)

Puglia region is in the heel of Italy’s boot and boasts stunning coastlines, scenic towns, and rich cultural heritage.

A road trip through Puglia is the perfect way to explore this beautiful region and discover hidden gems. 

So, find a detailed 7-day road trip itinerary for this beautiful region below for a memorable experience.

Day 1: Bari

Bari is Puglia’s capital, making it a great spot to start your road trip. 

On the first day, explore the charming old town of Bari, known as Bari Vecchia. Wander through narrow alleys, admire beautiful architecture, and visit the stunning Basilica di San Nicola, which houses the remains of Saint Nicholas. 

Don’t miss the opportunity to try delicious street food, such as focaccia barese and panzerotti. And later in the evening, head to the lively Piazza del Ferrarese to enjoy a drink in a vibrant environment.

Day 2: Bari to Polignano Mare

Head south to Polignano Mare, a picturesque town perched on a cliff overlooking the Adriatic Sea. 

Stroll through the charming old town and admire the stunning seascapes from the terraces. Also, be sure to visit the famous Grotta Palazzese, a restaurant built inside a natural cave overlooking the sea. 

In the afternoon, head to the nearby pebbly beach of Lama Monachile, also known as the “Cala Porto,” to relax, sunbathe, and swim in pristine azure waters.

Day 3: Polignano Mare to Locorotondo via Alberobello

On the third day, head to Alberobello, a UNESCO-listed town famous for its unique trulli houses. Stroll around charming alleys to admire the architecture and learn more about the town’s history.

Afterward, continue your journey to Locorotondo, a charming hilltop town known for its white-washed houses and winding streets. So, take a leisurely walk through the town’s historic center and enjoy the panoramic views of the surrounding countryside.

Day 4: Locorotondo to Ostuni via Martina Franca

Head towards Martina Franca, a lovely town known for its Baroque architecture and lively atmosphere. Stroll through the historic center and marvel at the ornate buildings and charming piazzas.

After exploring Martina Franca, drive to Ostuni, also known as the “White City,” due to its white-washed buildings. Walk through narrow alleys and enjoy gorgeous rural views from the top of the hill. 

Day 5: Ostuni to Lecce

Head towards Lecce, a city known for its stunning Baroque architecture and rich cultural heritage. 

Immerse in the city’s lovely ambiance and visit beautiful landmarks, including Basilica di Santa Croce. Also, stop by Piazza del Duomo and marvel at the intricate details of the cathedral’s facade. 

In the evening, head to one of Lecce’s many restaurants and indulge in the region’s delicious cuisine, such as orecchiette pasta with tomato sauce and ricotta cheese.

Day 6: Day Trip to Torre dell’Orso

Take a day trip to Torre dell’Orso, a scenic seaside town located on the Adriatic coast. 

Spend the day lounging on the sandy beach, soaking up the sun and swimming in the crystal-clear waters. Stroll along the promenade and admire the stunning views of the surrounding cliffs and rock formations.

Plenty of water sports activities are available for adventure seekers, like kayaking and windsurfing.

Day 7: Lecce to Bari

On the last day, drive back to Bari for your flight or even take a ferry home. However, if you have time, stop by Brindisi, Monopoli, or Castella Grotte.

Brindisi is a charming port town with a rich history to explore through impressive attractions.

Monopoli is a lovely coastal town with beautiful beaches and a stunning cathedral.

Castellana Grotte is home to some of the most impressive caves in Italy.